Aims

Everyone has an innate immune response regardless of what stage you are at in health, illness or recovery.  What we are measuring here is how your body is currently responding in its effort to maintain homeostasis.   Most people have heard of ‘adrenal fatigue’ but this test will help us know whether it has reached the stage where it is causing unrelenting tiredness, poor digestion, poor sleep and other hormonal imbalances.  Eating until you are no longer hungry does not mean that you are getting the nutrients and energy you need at a cellular level.  Many people who eat a Western diet are, in fact, malnourished. this test will aim to find out why you feel so fatigued, low in energy and motivation, have mood swings, feel tearful etc.

  • Have you got the basic nutrients your body’s systems need to function optimally?
  • Is your body adapting appropriately to the stress in your life, or is it having a knock-on effect on other body systems?
  • Which nutrients or supplements do you currently need to take short-term to rectify any imbalances?

Lab Tests in the Bronze Package

Adrenal Stress Profile

This is a comprehensive tool to assess the HPA Axis — Stress Response and Resiliency

The Adrenal Stress Profile (ASP) provides an assessment of the Hypothalamic-Pituitary-Adrenal (HPA) axis using carefully timed salivary samples of the hormones cortisol and DHEA. Salivary testing is an easy, non-invasive option to measure unbound, biologically active parent hormone levels. The report offers an easy-to-interpret graphic which plots the results of cortisol’s natural diurnal rhythm.

DHEA is measured once in the 7:00 – 9:00 AM sample and a ratio of DHEA to cortisol is calculated to provide insight into anabolic/catabolic balance.

Daily hassles, chronic pain, blood sugar dysregulation, work stressors, and poor relationship quality can alter the HPA axis. Imbalances in adrenal hormones can have a wide range of negative consequences that can adversely impact a patient’s overall quality of life. The symptoms of HPA axis dysfunction can be vague, and are highly variable, but may include: fatigue, insomnia, weight gain, depression, GI complaints, and chronic pain. HPA axis dysfunction is associated with many conditions including:

  • hypertension
  • cardiovascular disease
  • gastrointestinal and immune dysregulation
  • diabetes and metabolic syndrome
  • depression
  • chronic fatigue
  • persistent pain
  • neurodegenerative disease and cognitive decline

Adrenal Stress Profile testing can reveal these HPA axis imbalances and provide direction for clinical intervention with targeted therapeutic treatments, such as nutrient support and/or adaptogens, stress management, behavioral modification, and lifestyle interventions.

Metabolic Analysis Profile

The Metabolic Analysis Profile report categorizes test results into major metabolic areas:

  • Metabolic Analysis Markers
  • Cellular Energy & Mitochondrial Metabolites
  • Neurotransmitter Metabolites
  • Vitamin Markers
  • Toxin & Detoxification Markers
  • Tyrosine Metabolism

How is it Tested?

first morning urine sample

Included Programmes

  • Functional Medicine Discovery Consultation
  • Lab Results Review and Consultation
  • Functional Medicine Timeline: how you got to where you are now
  • Functional Medicine Matrix
  • 7-day introduction to Functional Nutrition
  • Adrenal Stress Profile (lab test)
  • Metabolic Analysis Profile (lab test)

Who might benefit from organic acid testing according to the research?

Metabolic Analysis Profile testing is effective for patient concerns such as:

  • Mood Disorders (footnotes 1,2)
  • Mitochondrial Dysfunction (3)
  • Fatigue (4)
  • Chronic Stress( 5)
  • Inflammation (6)

Several diseases are associated with abnormal organic acid levels such as depression, anxiety, cardiovascular disease, neurocognitive decline, diabetes, cancer, anorexia, and many others.

 

Booking Provided by Healthie

 

    1. Lykouras L, Markianos M, Hatzimanolis J, Malliaras D, Stefanis C. Association of biogenic amine metabolites with symptomatology in delusional (psychotic) and nondelusional depressed patients. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 1995;19(5):877-887. https://www.ncbi.nlm.nih.gov/pubmed/8539425
    2. Frankenhaeuser M, Lundberg U, Von Wright MR, Von Wright J, Sedvall G. Urinary monoamine metabolites as indices of mental stress in healthy males and females. Pharmacol Biochem Behav. 1986;24(6):1521-1525. https://www.ncbi.nlm.nih.gov/pubmed/8539425
    3. Mitochondrial Medicine Society’s Committee on D, Haas RH, Parikh S, et al. The in-depth evaluation of suspected mitochondrial disease. Mol Genet Metab. 2008;94(1):16-37. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810849/
    4. Dimmock DP, Lawlor MW. Presentation and Diagnostic Evaluation of Mitochondrial Disease. Pediatr Clin North Am. 2017;64(1):161-171. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130109/
    5. Wu H, Jiang K, Gu G, Wu Y, Yu S. [The relationship of occupational stress and the level of some hormone metabolites in urine]. Chinese J Indust Hyg Occup Dis. 2014;32(2):83-86. https://www.ncbi.nlm.nih.gov/pubmed/24630003
    6. Jeon SW, Kim Y-K. Inflammation-induced depression: Its pathophysiology and therapeutic implications. J Neuroimmunol. 2017;313:92-98. https://www.ncbi.nlm.nih.gov/pubmed/29153615